Fig. 5
From: PSAT1 inhibits ferroptosis in osteosarcoma cells by activating the Xct/GPX4 signaling axis
Overexpression of PSAT1 promoted tumor proliferation, migration and invasion. (A) PSAT1 mRNA content after transferring into PSAT1 overexpression plasmid. (B) PSAT1 protein after transferring into PSAT1 overexpression plasmid. (C) The effect of overexpression of PSAT1 on the migratory capacity of 143B and MG-63 cells was verified by the cell scratch method. (D,E) The effect of overexpression of PSAT1 on the invasive and migratory capacity of 143B and MG-63 cells was verified by the Treswell chamber method. (F,G) Effect of PSAT1 overexpression on the cycle of 143B and MG-63 cells. pCMV-PSAT1: overexpression PSAT1 group; pCMV-MCS: control group. *p < 0.05; **p < 0.01; ***p < 0.001.
