Table 3 Effect of physical activity by level on tuberculosis development.

From: Physical activity intensity and amount are inversely correlated with the risk of tuberculosis in patients with diabetes

METs-Min/week

n

TB

Duration (PY)

IR (per 1000 PY)

Adjusted hazard ratio (95% confidence interval)

Model 1

Model 2

Model 3

Model 4

< 500

1,316,295

11,991

8,972,552.81

1.34

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

500–999

611,800

5,136

4,218,223.59

1.22

0.91 (0.88, 0.94)

0.90 (0.87, 0.93)

0.91 (0.88, 0.94)

0.91 (0.88, 0.94)

1000–1499

257,265

1,998

1,796,191.17

1.11

0.83 (0.79, 0.87)

0.82 (0.78, 0.86)

0.85 (0.81, 0.89)

0.85 (0.81, 0.90)

≥ 1500

252,083

2,150

1,757,527.91

1.22

0.92 (0.87, 0.96)

0.81 (0.78, 0.85)

0.83 (0.80, 0.87)

0.84 (0.80, 0.88)

  1. Model 1: non-adjusted.
  2. Model 2: adjusted for age and sex.
  3. Model 3: adjusted for age, sex, body mass index, income, smoking, drinking, hypertension, and dyslipidemia.
  4. Model 4: adjusted for age, sex, body mass index, income, smoking, drinking, hypertension, dyslipidemia, fasting glucose, chronic kidney disease, diabetes mellitus duration (< 5 vs. ≥ 5 years), oral hypoglycemic agents (< 3 vs. ≥ 3), and insulin use.
  5. TB: tuberculosis; PY: person-year; IR: incidence rate; Ref.: reference; METs-min/week: metabolic equivalent task minutes per week.