Fig. 7 | Scientific Reports

Fig. 7

From: NFIC suppressed the epithelial ovarian cancer via modulating the balance of PTEN/TGFβ1/EGR1/BRD4 and SP1/EZH2 induced Inhibition of TBX2/MMPs signaling

Fig. 7

NFIC mediates STAT3/TGFβ1 inhibition of ovarian cancer cell proliferation. A: Western blot protein banding plots of P-PI3K, CyclinA1, CyclinD1 as well as statistical plots of relative protein expression in NC group, NFIC-OE group, NFIC-OE + TBX2-OE group, NFIC-OE + SF1670 group and NFIC-OE + SF1670 + TGFβ1-IN-1 group; B: CCK-8 assay results for SKOV3, OVCAR-3, and A2780 cells; C: Results of cloning formation experiments and statistical graphs of clone numbers for SKOV3, OVCAR-3, and A2780 cells. GAPDH as control protein; Data are expressed as mean ± standard deviation. N = 3; **P<0.01.

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