Fig. 3 | Scientific Reports

Fig. 3

From: Comprehensive multi-omics and machine learning framework for glioma subtyping and precision therapeutics

Fig. 3

Comprehensive somatic-mutation landscape in Glioma. (A) Driver-gene mutation bar charts across CS1–3. (B) Stacked exposure of COSMIC v3.4 single-base-substitution signatures per sample. (C) Violin plot comparing SBS1 exposure among clusters. (D–F) OncoPrints for CS1-3, respectively (top 10 mutated genes). (G–I) Pairwise co-occurrence/ exclusivity matrices for CS1-3. (J) Heat-map of driver-gene mutation frequency by cluster. (K) Neo-antigen load per cluster.

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