Fig. 2
From: Permissiveness of American bison to infection with severe acute respiratory syndrome coronavirus-2
Photomicrographs of lung from bison #304 intranasally infected with SARS-CoV-2 and examined 5 days later. (A) Note expanded alveolar interstitium in left side of image. Multifocally, interstitial infiltrates included numerous neutrophils (inset). Bar = 200 µm. (B) Amphophilic to eosinophilic proteinaceous material (arrows) fills multiple alveolar lumens consistent with pulmonary edema. Bar = 100 µm. (C) Note perivascular infiltrates of lymphocytes (arrow). Bar = 100 µm. (D) Some alveolar lumens contain irregular aggregates of fibrillar and flocculent eosinophilic material consistent with fibrin (arrows). Bar = 20 µm. H&E.
