Fig. 3
From: Permissiveness of American bison to infection with severe acute respiratory syndrome coronavirus-2
Photomicrographs of ISH labeling for SARS-CoV-2 RNA in sections of medial retropharyngeal lymph nodes (A; Bison #9, B; Bison #190) and lung (C; Bison #304, D; Bison #191) of bison inoculated intranasally with SARS-CoV-2 and examined 5 days (A, C) and 21 days (B, D) p.i.. Red labeling indicates presence of viral RNA. Labeling 5 days p.i. (A, C) was greater and more intense than labeling at 21 days p.i. (B, D), which was generally characterized by individual cells containing one to several dots each (arrows). Viral RNA was not detected in tissues of non-infected control bison. Bar = 200 µm (A, B, C), Bar = 20 µm (D). GC = germinal center; ISH SARS-CoV-2.
