Table 2 Age according to epigenetic clocks (in years; means and standard deviations).

From: Epigenetic aging acceleration among World Trade Center-exposed community members

 

WTC-exposed

WTC-unexposed

p-value

Chronological age

58.4 (7.6)

53.3 (7.2)

< 0.0001

Hannum age

68.9 (6.3)

63.0 (6.6)

< 0.0001

Horvath age

65.3 (5.8)

61.1 (7.0)

< 0.0001

PhenoAge

52.0 (8.0)

48.0 (8.4)

0.0015

GrimAge

74.9 (6.5)

74.0 (6.3)

0.3402

  1. *β coefficients for WTC exposed vs. unexposed from the statistical OLS models; denotes statistical significance (p < 0.05); Adjusted for race, BMI, smoking status, cancer status, cell type composition (CD8T cells, CD4T cells B cells, NK cells, B cells, Monocytes), batch. Unit is years.