Table 2 Multivariable Cox proportional hazards regression analysis for the association between CTI and all-cause and cardiovascular mortality.

From: Association of C reactive protein triglyceride glucose index with mortality in coronary heart disease and type 2 diabetes from NHANES data

Variables

Groups

Model 1

Model 2

Model 3

HR (95%CI)

P

HR (95%CI)

P

HR (95%CI)

P

All-cause mortality

      

CTI

Continuous

1.27 (1.16–1.38)

< 0.001

1.59 (1.42–1.78)

< 0.001

1.68 (1.47–1.92)

< 0.001

 

Q1 (< 8.18)

1.00 (Ref)

 

1.00 (Ref)

 

1.00 (Ref)

 
 

Q2 (8.18–8.69)

1.14 (0.88–1.48)

0.331

1.36 (1.02–1.80)

0.037

1.46 (1.09–1.95)

0.011

 

Q3 (8.69–9.24)

2.05 (1.60–2.63)

< 0.001

2.83 (2.08–3.85)

< 0.001

3.15 (2.29–4.34)

< 0.001

 

Q4 (≥ 9.24)

1.73 (1.34–2.22)

< 0.001

2.89 (2.10–3.98)

< 0.001

3.07 (2.17–4.34)

< 0.001

P for trend

  

< 0.001

 

< 0.001

 

< 0.001

Cardiovascular mortality

      

CTI

Continuous

1.30 (1.13–1.48)

< 0.001

1.67 (1.40–2.00)

< 0.001

1.70 (1.38–2.10)

< 0.001

 

Q1 (< 8.18)

1.00 (Ref)

 

1.00 (Ref)

 

1.00 (Ref)

 
 

Q2 (8.18–8.69)

0.92 (0.60–1.40)

0.689

1.08 (0.69–1.71)

0.727

1.13 (0.71–1.81)

0.599

 

Q3 (8.69–9.24)

1.89 (1.29–2.76)

0.001

2.44 (1.51–3.94)

< 0.001

2.51 (1.51–4.16)

< 0.001

 

Q4 (≥ 9.24)

1.71 (1.17–2.51)

0.006

2.79 (1.71–4.57)

< 0.001

2.75 (1.60–4.72)

< 0.001

P for trend

  

< 0.001

 

< 0.001

 

< 0.001

  1. Model1: Unadjusted
  2. Model2: adjusted for Age, Gender, Race, Education, Drink, CKM syndrome, BMI, WC
  3. Model3: adjusted for Model2 + Heart failure, Frailty status, SBP, TC, HbA1c, eGFR, HDL-C
  4. CTI, C-reactive protein-triglyceride-glucose index; BMI, Body mass index; CKM, Cardiovascular-Kidney-Metabolic syndrome; WC, Waist circumference; SBP, Systolic blood pressure; TC, Total cholesterol; HbA1c, Glycated hemoglobin; eGFR, estimated glomerular filtration rate; HDL-C, High-density lipoprotein cholesterol; HR: Hazard Ratio, CI: Confidence Interval
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