Fig. 2 | Scientific Reports

Fig. 2

From: Single-cell RNA sequencing analysis revealed the immunosuppressive remodeling of tumor-associated macrophages mediated by the MIF-CD74 axis in gastric cancer

Fig. 2

Different macrophage subpopulations in gastric cancer. (A) Differential expression analysis of genes associated with M2 polarization, immunosuppression, invasion, recruitment, and M1 polarization in macrophage cluster. (B) Heatmap showing the top DEGs in each macrophage subtype. (C) UMAP plots show marker genes in different macrophage clusters. (D) KEGG analysis in different macrophage subtypes. (E) GO analysis in different macrophage subtypes. (F) Ligand receptor pairs of the signaling pathway network from tumor to macrophage were analyzed by CellChat. Dot color reflects communication probabilities, and dot size represents computed p-values. Empty space means the communication probability is zero.

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