Fig. 8

Cartoon representation: overlay of the crystal structures of TIMP1 protein with small molecule compounds meclizine and megestrol.(A) Cartoon representation of molecular docking and interaction of TIMP1 with meclizine; (B)Cartoon representation of molecular docking and interaction of TIMP1 with megestrol; (C)The 3D structure of TIMP1 protein; (D)The 3D structure of meclizine; (E)The 3D structure of megestrol.