Table 4 Associated factors for OS and CSS in patients with chondroblastic osteosarcoma.

From: Survival profiles and associated factors for overall and cancer specific survival in patients with chondroblast and fibroblastic osteosarcoma

Variables

OS

CSS

HR (95% CI)

P values

HR (95%CI)

P values

Age

    

 < 30

1.00 (Reference)

 

1.00 (Reference)

 

 ≥ 30

2.09 (1.56—2.81)

 <.001

1.67 (1.23—2.27)

0.001

Race

    

 Non-Hispanic White

1.00 (Reference)

 

/

/

 Non-Hispanic Black

1.41 (1.01—1.96)

0.04

/

/

 Other

1.15 (0.71—1.86)

0.58

/

/

First Cancer

    

 Yes

1.00 (Reference)

 

/

/

 No

0.39 (0.16—0.97)

0.04

/

/

Primary site

    

 No

1.00 (Reference)

 

/

/

 Yes

0.24 (0.09—0.62)

0.003

/

/

T Stage

    

 T1

1.00 (Reference)

 

1.00 (Reference)

 

 T2-T4

1.61 (1.15—2.24)

0.005

1.91 (1.30—2.83)

0.001

 TX

1.33 (0.85—2.08)

0.21

1.39 (0.80—2.41)

0.240

N Stage

    

 N0

1.00 (Reference)

 

1.00 (Reference)

 

 N1

1.85 (0.94—3.61)

0.07

1.93 (0.99—3.78)

0.055

 NX

0.82 (0.49—1.37)

0.44

1.02 (0.55—1.86)

0.960

M Stage

    

 M0

1.00 (Reference)

 

1.00 (Reference)

 

 M1

2.57 (1.80—3.67)

 <.001

2.96 (2.03—4.32)

 <.001

 MX

1.26 (0.41—3.81)

0.69

1.27 (0.35—4.65)

0.710

Radiation

    

 No/Unknown

1.00 (Reference)

 

1.00 (Reference)

 

 Yes

1.24 (0.88—1.77)

0.22

1.34 (0.91—1.96)

0.130

Chemotherapy

    

 No/Unknown

1.00 (Reference)

 

1.00 (Reference)

 

 Yes

0.65 (0.45—0.93)

0.02

0.67 (0.43—1.07)

0.093

Surgery

    

 No

1.00 (Reference)

 

1.00 (Reference)

 

 Yes

0.28 (0.20—0.40)

 <.001

0.35 (0.25—0.51)

 <.001

  1. OS: Overall survival; CSS: Cancer specific survival; HR: Hazard Ratio, CI: Confidence Interval.
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