Table 2 Results of quality assessment of cohort studies.

From: Comparison between long-acting pegylated and daily recombinant human growth hormone for pediatric growth hormone deficiency a systematic review

Study ID

Qiao 2019

Chen 2019

Wan 2021

Yang 2022

Selection

Representativeness of exposed cohort

a) Truly representative of average condition in community

b) Somewhat representative of average condition in community

c) Selected group of users, e.g., nurses, volunteers

d) No description of derivation of cohort

b)

b)

b)

b)

Selection of non-exposed cohort

a) Drawn from same community as exposed cohort

b) Drawn from different source

c) No description of derivation of non-exposed cohort

a)

a)

a)

a)

Ascertainment of exposure

a) Secure records (e.g., surgical records)

b) Structured interview

c) Written self-report

d) No description

a)

a)

a)

a)

Demonstration that outcome of interest not present at start of study

a) Yes

b) No

a)

b)

b)

b)

Comparability

Comparability of cases and controls on basis of design or analysis

a) Study controls for age

b) Study controls for any additional factor

a)

a)

a)

b)

Outcome

Assessment of outcome

a) Independent blind assessment

b) Record linkage

c) Self-report

d) No description

b)

b)

b)

b)

Was follow-up long enough for outcomes to occur?

a) Yes

b) No

a)

a)

a)

a)

Adequacy of follow-up of cohorts

a) Complete follow-up: all subjects accounted for

b) Small number (< 20%) lost to follow-up, unlikely to introduce bias, or description provided of those lost

c) Follow-up rate > 20% and no description of those lost

d) No statement

b)

a)

a)

a)

Total

  

9

8

8

8