Table 3 Summarized results of randomized controlled trials.

From: Comparison between long-acting pegylated and daily recombinant human growth hormone for pediatric growth hormone deficiency a systematic review

Outcome

Time point

No. of included studies

Sample size of PEG-rhGH group

Sample size of daily rhGH group

Mean difference (95%CI)

p value

Change in height (SDS)

6 m

5

485

404

0.02 (−0.02, 0.07)

0.32

Change in HV (cm/y)

6 m

3

281

189

0.30 (−0.31, 0.91)

0.34

IGF-1 (SDS)

6 m

2

53

74

0.13 (−0.14, 0.39)

0.34

Change in IGF-1 (SDS)

6 m

3

240

250

0.33 (0.16, 0.51)

0.0002

Change in IGF-1 (ng/mL)

6 m

1

17

39

−12.59 (−108.29, 83.11)

0.80

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