Fig. 8
From: Hyperglycemia-induced mitochondrial abnormalities in autonomic neurons via the RAGE axis
Colocalization of RAGE and ATPB in the neurites of cultured SCG neurons. A-B, Representative images of immunocytochemical colocalization of RAGE and the mitochondrial marker ATPB in neurites of SCG neurons maintained in either control (CTL, A) or high glucose (HG, B). The inset image show a zoomed-in area depicting a mitochondrion and puncta RAGE staining. Scale bar = 2 μm. C-D, Bar graphs show the Pearson’s and Mandel’s coefficients obtained for the colocalization of RAGE and ATPB in the neurites of SCG neurons maintained in CTL or HG conditions. Means were statistically compared by Student’s t-test; p > 0.05. (N = 3 per group).
