Fig. 6

ATXF inhibited the proliferation, migration and invasion of HCC cells. Inhibition and survival of (A) HCCLM3 (B) MHCC97L (C) HepG2 at different time points after different concentrations of ATXF. (D) The colony formation was visualized by microscopy after ATXF treatments (14 days at 0, 50, and 100 mg/mL). (E) Transwell assay for three cells treated with different concentration of ATXF and relative quantification cell number. Data are presented as the mean ± SD (n = 3, ***p < 0.001). ****, p < 0.0001, ####, p < 0.0001).