Table 3 Inhibitory effect of BBR combined with β-lactam antibiotics on USA300 (µg/mL).

From: Mechanistic studies on the effect of berberine on methicillin-resistant Staphylococcus aureus drug resistance through modulation of wall teichoteic acid

Strains

MIC (ug/mL)

BBR

Oxacillin

BBR + Oxacillin

Methicillin

BBR + Methicillin

Cefotaxime

BBR + Cefotaxime

USA300

128

32

64 + 8

32

64 + 8

128

64 + 16

▲tarS

128

16

32 + 4

16

32 + 4

32

64 + 2

▲tarM

128

16

32 + 4

16

32 + 4

32

64 + 2

▲tarO

64

0.016

16 + 0.008

0.032

16 + 0.008

2

16 + 0.25

▲tarSM

128

4

32 + 1

4

32 + 1

4

32 + 1

R-tarS

128

32

32 + 16

32

32 + 16

128

64 + 32

R-tarM

128

32

32 + 16

32

32 + 16

128

64 + 32

R-tarO

128

32

32 + 16

32

32 + 16

128

64 + 32

R-tarSM

128

32

32 + 16

32

32 + 16

128

64 + 32