Table 1 Basal characteristics of the patients at the time of liver transplantation.

From: Pre-transplant predictors of 3-Month survival following liver transplantation for acute liver failure in adult and pediatric patients in Türkiye

 

Total

Pediatric

Adult

p

n

336

100

236

 

Age (year)

27.7 (24.9–29.5)

7.5 (5.5–8.6)

33.7 (32.0-36.8)

 

Gender Female, n (%)

191 (56.8)

48 (48.0)

143 (60.6)

0.022

BMI

23.4 (22.9–24.2)

17.5 (16.6–17.9)

24.5 (24.1–25.1)

< 0.001

Total bilirubin (mg/dl)

16.0 (14.2–17.8)

17.5 (12.2–21.8)

15.6 (14.0-17.3)

0.968

Albumin (g/dl)

3.0 (3.0-3.1)

3.3 (3.1–3.4)

2.9 (2.8-3.0)

< 0.001

INR

3.3 (3.1–3.6)

3.3 (3.0-3.8)

3.3 (3.0-3.6)

0.106

Creatinine (mg/dl)

0.60 (0.60–0.66)

0.49 (0.43–0.50)

0.70 (0.64–0.70)

< 0.001

Sodium (mEq/l)

138 (137–138)

138 (137–138)

137 (137–138)

0.537

Arterial lactate (mmol/l)

3.33 (3.11–3.75)

4.00 (3.20–4.87)

3.22 (3.11–3.55)

0.104

Arterial ammonia (µmol/l)

206 (184–220)

131 (107–175)

231 (217–245)

< 0.001

Arterial pH

7.40 (7.40–7.40)

7.40 (7.39–7.40)

7.40 (7.40–7.40)

0.332

PELD/MELD score

31 (30–32)

30 (28–32)

31 (30–32)

0.265

Time from listing to LT (day)

4 (4–4)

3 (2–3)

4 (4–5)

< 0.001

HE Stages, n (%)

   

< 0.001

1

13 (3.9)

5 (5.0)

8 (3.4)

 

2

73 (21.7)

30 (30.0)

43 (18.2)

 

3

130 (38.7)

44 (44.0)

86 (36.4)

 

4

102 (30.4)

13 (13.0)

89 (37.7)

 

Not defined

18 (5.4)

8 (8.0)

10 (4.2)

 

Transplant type, n (%)

   

< 0.001

LDLT

221 (65.8)

86 (86.0)

135 (57.2)

 

DDLT

115 (34.2)

14 (14.0)

101 (42.8)

 

Etiologies, n (%)

    

Viral

91 (27.1)

15 (15.0)

76 (32.2)

0.001

Hepatitis A

18 (19.8)

11 (73.3)

7 (9.2)

< 0.001

Hepatitis B

69 (75.8)

2 (13.3)

67 (88.2)

Hepatitis C

1 (1.1)

-

1 (1.3)

 

EBV

1 (1.1)

-

1 (1.3)

 

Parvovirus

1 (1.1)

1 (6.7)

-

 

Adenovirus

1 (1.1)

1 (6.7)

-

 

DILI

68 (20.2)

24 (24.0)

44 (18.6)

0.299

Indeterminate

102 (30.4)

38 (38.0)

64 (27.1)

0.052

Budd-Chiari syndrome

7 (2.1)

-

7 (3.0)

0.109

Pregnancy-related

4 (1.2)

-

4 (1.7)

 

HELLP Syndrome

3 (75.0)

 

3 (75.0)

 

Acute Fatty Liver

1 (25.0)

 

1 (25.0)

 

Childhood diseases*

2 (0.6)

2 (2.0)

-

 

Hemochromatosis

1 (0.3)

-

1 (0.4)

 

Autoimmune hepatitis

9 (2.7)

2 (2.0)

7 (3.0)

1.000

Wilson’s disease

23 (6.8)

12 (12.0)

11 (4.7)

0.031

Mushroom

25 (7.4)

7 (7.0)

18 (7.6)

1.000

Acute ischemic injury

4 (1.2)

-

4 (1.7)

 
  1. * Childhood diseases were metabolic disease (n = 1) and Infantile Liver Failure Syndrome Type 1 (n = 1).
  2. LT, liver transplantation; BMI, body mass index; INR, international normalized ratio; MELD, model for end-stage liver disease; PELD, pediatric end-stage liver disease; HE, hepatic encephalopathy; LDLT, living donor liver transplantation; DDLT, deceased donor liver transplantation; EBV, Epstein-Bar virus; DILI, drug-induced liver injury; HELLP, haemolysis, elevated liver enzymes, and low platelets.
  3. Data are presented as median (95% confidence interval) unless otherwise indicated.
Back to article page