Table 1 Baseline characteristics of the patients with sepsis.
Characteristics | Overall (n = 2673) | Non-ARC (n = 2155) | ARC (n = 518) | P value |
|---|---|---|---|---|
Age, (years) | 67.00 [55.00, 77.00] | 68.00 [57.50, 79.00] | 58.00 [46.00, 71.00] | < 0.001 |
Weight, median [IQR] | 79.90 [66.20, 96.80] | 80.00 [66.43, 97.50] | 77.07 [65.60, 93.54] | 0.038 |
Ethnicity, n (%) | 0.005 | |||
White | 1790 (67.0) | 1461 (67.8) | 329 (63.5) | |
Black | 254 (9.5) | 216 (10.0) | 38 (7.3) | |
Latino | 100 (3.7) | 81 (3.8) | 19 (3.7) | |
Asian | 67 (2.5) | 52 (2.4) | 15 (2.9) | |
Other | 462 (17.3) | 345 (16.0) | 117 (22.6) | |
CCI | 5.00 [3.00, 8.00] | 6.00 [4.00, 8.00] | 4.00 [2.00, 5.00] | < 0.001 |
Peripheral vascular disease, n (%) | 311 (11.6) | 285 (13.2) | 26 (5.0) | < 0.001 |
Diabetes, n (%) | 834 (31.2) | 741 (34.4) | 93 (18.0) | < 0.001 |
Renal disease, n (%) | 740 (27.7) | 723 (33.5) | 17 (3.3) | < 0.001 |
Mechanical ventilation, n (%) | 1735 (64.9) | 1354 (62.8) | 381 (73.6) | < 0.001 |
MBP min, (mmHg) | 58.00 [50.00, 66.00] | 57.00 [49.00, 65.00] | 61.00 [52.00, 70.00] | < 0.001 |
MBP max, (mmHg) | 102.00 [91.00, 117.00] | 101.00 [90.00, 115.25] | 106.00 [95.00, 121.00] | < 0.001 |
PCO2 min, (mmHg) | 37.00 [30.00, 45.00] | 36.00 [29.00, 44.00] | 38.00 [33.00, 49.00] | < 0.001 |
PCO2 max, (mmHg) | 43.00 [34.00, 53.00] | 43.00 [34.00, 53.00] | 43.00 [35.00, 53.00] | 0.971 |
Total CO2 min, (mmHg) | 22.00 [17.00, 27.00] | 22.00 [17.00, 26.00] | 24.00 [20.00, 27.00] | < 0.001 |
Total CO2 max, (mmHg) | 24.00 [15.00, 28.00] | 23.00 [11.00, 27.00] | 25.00 [21.00, 29.00] | < 0.001 |
RBC min, (10^12/L) | 3.64 [3.06, 4.23] | 3.55 [3.00, 4.14] | 3.97 [3.41, 4.57] | < 0.001 |
RBC max, (10^12/L) | 3.79 [3.29, 4.35] | 3.71 [3.22, 4.27] | 4.14 [3.64, 4.67] | < 0.001 |
RDW min, (%) | 15.10 [13.90, 17.10] | 15.40 [14.10, 17.35] | 14.20 [13.30, 15.60] | < 0.001 |
RDW max, (%) | 15.40 [14.10, 17.40] | 15.70 [14.40, 17.70] | 14.40 [13.50, 15.80] | < 0.001 |
Neutrophil min, (10^9/L) | 8.47 [4.33, 13.74] | 8.65 [4.41, 14.00] | 7.80 [4.06, 12.52] | 0.021 |
Neutrophil max, (10^9/L) | 10.16 [5.46, 16.00] | 10.20 [5.50, 16.07] | 10.00 [5.44, 15.27] | 0.436 |
Hb min, median [IQR] | 10.70 [9.10, 12.50] | 10.40 [8.90, 12.20] | 11.78 [10.11, 13.50] | < 0.001 |
Hb max, median [IQR] | 11.20 [9.70, 12.90] | 10.95 [9.55, 12.65] | 12.30 [10.80, 13.99] | < 0.001 |
PLT min, median [IQR] | 209.00 [140.00, 286.00] | 204.00 [134.00, 283.50] | 225.00 [162.00, 301.75] | < 0.001 |
PLT max, median [IQR] | 225.00 [154.00, 301.00] | 221.00 [150.00, 297.00] | 235.00 [174.25, 309.75] | < 0.001 |
INR min | 1.30 [1.10, 1.70] | 1.30 [1.20, 1.80] | 1.20 [1.10, 1.40] | < 0.001 |
INR max | 1.40 [1.20, 2.00] | 1.50 [1.20, 2.10] | 1.30 [1.10, 1.50] | < 0.001 |
Ca min, median [IQR] | 6.70 [4.62, 8.40] | 7.10 [4.66, 8.40] | 5.16 [4.53, 8.20] | < 0.001 |
Ca max, median [IQR] | 7.20 [4.88, 8.60] | 7.50 [4.90, 8.70] | 5.30 [4.82, 8.50] | 0.001 |
BUN min, (mg/dL) | 26.00 [16.00, 44.00] | 30.00 [19.00, 49.00] | 16.00 [12.00, 21.00] | < 0.001 |
BUN max, (mg/dL) | 29.00 [18.00, 47.00] | 33.00 [22.00, 52.00] | 17.00 [13.00, 23.00] | < 0.001 |
Serum creatinine min, (mg/dL) | 1.30 [0.90, 1.90] | 1.40 [1.00, 2.10] | 0.90 [0.70, 1.10] | < 0.001 |
Serum creatinine max, (mg/dL) | 1.40 [1.00, 2.10] | 1.60 [1.10, 2.30] | 0.90 [0.70, 1.20] | < 0.001 |
ALP min, (U/L) | 106.00 [66.00, 182.00] | 108.00 [69.00, 182.00] | 94.00 [59.00, 182.00] | 0.010 |
ALP max, (U/L) | 107.00 [69.00, 162.00] | 107.00 [71.50, 162.00] | 101.00 [62.00, 158.75] | 0.016 |
ALT min, (U/L) | 30.00 [15.00, 73.00] | 30.00 [16.00, 73.00] | 28.00 [14.00, 66.75] | 0.090 |
ALT max, (U/L) | 30.00 [18.00, 65.00] | 30.00 [18.00, 65.50] | 30.00 [17.00, 65.00] | 0.870 |
AST min, (U/L) | 49.00 [27.00, 115.00] | 50.00 [27.00, 117.50] | 48.00 [26.25, 110.00] | 0.563 |
AST max, (U/L) | 53.00 [28.00, 134.00] | 54.00 [28.00, 138.00] | 50.00 [27.00, 116.75] | 0.437 |
