Table 7 Determination of lacidipine in Lacirex tablet by the proposed first derivative synchronous spectrofluorimetric and reported methods * Reported method is a spectrophotometric method which is based on the reaction of lacidipine with ferric chloride, potassium ferricyanide and hydrochloric acid to form a bluish green colored chromogen with an absorption maximum at 740 nm. ** the values in parenthesis are tabulated values of “t” and “F” at (P = 0.05).
Parameters | Proposed method | Reported method* |
|---|---|---|
Number of measurements | 5 | 5 |
Mean % recovery of lacidipine | 98.96 | 100.23 |
% RSD | 0.78 | 1.15 |
Variance | 0.6 | 1.33 |
Student’s t-test** | 2.056 (2.306) | —— |
F-value** | 2.243 (6.388) | —— |
