Fig. 2 | Scientific Reports

Fig. 2

From: Hydroxysafflor Yellow A modulation of metabolite networks and inhibition of JAK2/STAT1 pathway in sepsis

Fig. 2

HYSA protects multiple organs of mice from CLP-induced damage. (A) Protein content in BALF and MPO content in lung tissue. (B) ALT and AST expression levels in serum determined by biochemical analysis. (C) BUN and Crea expression levels in serum determined by biochemical analysis. (D) TNF-α and IL-6 expression levels in serum measured by ELISA. (E) Histopathology of lung, liver, and kidney using HE staining, scale bar = 200 μm. (F) Histopathological scores of lung, liver, and kidney. Data are presented as mean ± SD. ****P < 0.0001, ***P < 0.001, **P < 0.01 and *P < 0.05 vs. the CLP group. n = 3–4 mice per group.

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