Table 4 The information of metabolites in kidney profiles by using UPLC-MS/MS.(n = 8–10).
Number | Component | Formula | m/z | CLP vs.Sham | HYSA300 vs. CLP |
|---|---|---|---|---|---|
1 | L-Histidinol | C6H11N3O | 124.09 | ↓ | ↑ |
2 | PE(0:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) | C27H44NO7P | 526.29 | ↓ | ↑ |
3 | 3-Butenenitrile | C4H5N | 85.08 | ↓ | ↑ |
4 | N, N’-Diacetylhydrazine | C4H8N2O2 | 99.06 | ↓ | ↑ |
5 | 2,4-Diamino-Butyric Acid | C4H10N2O2 | 101.07 | ↓ | ↑ |
6 | 4,5-Dehydro Docosahexaenoic Acid | C22H30O2 | 344.26 | ↓ | ↑ |
7 | PE(0:0/16:0) | C21H44NO7P | 454.29 | ↓ | ↑ |
8 | Hydantoin | C3H4N2O2 | 101.03 | ↓ | ↑ |
9 | N-Methylhydantoin | C4H6N2O2 | 115.05 | ↓ | ↑ |
10 | 2-C-Methyl-D-Erythritol-4-Phosphate | C5H13O7P | 215.03 | ↓ | ↑ |
11 | PE(0:0/18:0) | C23H48NO7P | 480.31 | ↓ | ↑ |
12 | Miglustat | C10H21NO4 | 237.18 | ↓ | ↑ |
13 | 1-Methylhistamine | C6H11N3 | 126.10 | ↓ | ↑ |
14 | 3-Propyl-1 h-Pyrazole | C6H10N2 | 128.12 | ↓ | ↑ |
15 | 2,6-Dihydroxy-3-Cyanopyridine | C6H4N2O2 | 154.06 | ↓ | ↑ |
16 | Phosphate | C5H13O7P | 215.03 | ↓ | ↑ |
17 | Pyridine N-Oxide Glucuronide | C11H14NO7+ | 295.07 | ↓ | ↑ |
18 | N-Stearoyl Cysteine | C21H41NO3S | 370.28 | ↓ | ↑ |
19 | Alpha-L-Arabinofuranose | C5H10O5 | 195.05 | ↓ | ↑ |
20 | 2s-Amino-3-Oxo-Butanoic Acid | C4H7NO3 | 100.04 | ↓ | ↑ |
21 | 2-Aminobenzimidazole | C7H7N3 | 151.10 | ↓ | ↑ |
22 | Piperazine | C4H10N2 | 87.09 | ↓ | ↑ |
23 | Methylimidazole Acetaldehyde | C6H8N2O | 142.10 | ↓ | ↑ |
24 | D-Arabinono-1,4-Lactone | C5H8O5 | 193.04 | ↓ | ↑ |
25 | 4-Aminobenzamidine | C7H9N3 | 153.11 | ↓ | ↑ |
26 | N-Acetylhistamine | C7H11N3O | 154.10 | ↓ | ↑ |
27 | D-Psicose | C6H12O6 | 203.05 | ↓ | ↑ |
28 | Dl-Propargylglycine | C5H7NO2 | 131.08 | ↓ | ↑ |
29 | Aspartyl-Cysteine | C7H12N2O5S | 217.03 | ↓ | ↑ |
30 | Benzamidine | C7H8N2 | 138.10 | ↓ | ↑ |
31 | 3-Hydroxybutyrylcarnitine | C11H21NO5 | 248.15 | ↓ | ↑ |
32 | 1-Pyrimidinylpiperazine | C8H12N4 | 165.11 | ↓ | ↑ |
33 | Pyroglutamic Acid | C5H7NO3 | 130.05 | ↓ | ↑ |
34 | N1-Acetylspermidine | C9H21N3O | 188.18 | ↑ | ↓ |
35 | PS(18:2(9Z,12Z)/0:0) | C24H44NO9P | 522.28 | ↑ | ↓ |
36 | 2,5-Dimethylpyrazine | C6H8N2 | 126.10 | ↑ | ↓ |
37 | O-Acetylserine | C5H9NO4 | 128.04 | ↓ | ↑ |
38 | Acetyl-D-Carnitine | C9H17NO4 | 204.12 | ↓ | ↑ |
39 | D-Fructose | C6H12O6 | 219.03 | ↓ | ↑ |
40 | Isoleucylproline | C11H20N2O3 | 229.15 | ↑ | ↓ |
41 | PE(20:3(8Z,11Z,14Z)/0:0) | C25H46NO7P | 548.30 | ↓ | ↑ |
42 | Tyrosyl-Lysine | C15H23N3O4 | 310.18 | ↑ | ↓ |
43 | Methylphosphate | CH5O4P | 110.99 | ↓ | ↑ |
44 | Polyribosylribitolphosphate | C5H13O8P | 277.03 | ↓ | ↑ |
45 | PI(22:2(13Z,16Z)/6 keto-PGF1alpha) | C51H89O17P | 1027.58 | ↓ | ↑ |
46 | PE(17:0/0:0) | C22H46NO7P | 468.31 | ↓ | ↑ |
47 | Acetoacetic Acid | C4H6O3 | 147.03 | ↑ | ↓ |
48 | Glycine | C2H5NO2 | 76.04 | ↓ | ↑ |
49 | Hydralazine | C8H8N4 | 178.11 | ↓ | ↑ |
