Fig. 4 | Scientific Reports

Fig. 4

From: Vitamin B17 alleviates Sorafenib-induced cardiotoxicity in Ehrlich Ascites Carcinoma mice via modulation of inflammatory and fibrotic pathways

Fig. 4

Effects of Vitamin B17 (VB17) and/or Sorafenib (Sor) on oxidative stress and antioxidant defense markers in heart tissues of EAC-bearing mice. (A) Malondialdehyde (MDA) levels, (B) reduced glutathione (GSH), and (C) superoxide dismutase (SOD) activity. Treatments were administered via intraperitoneal (IP) or oral (O) routes. Data are presented as mean ± SEM (n = 6 per group). Statistical analysis was conducted using one-way ANOVA with Tukey’s post hoc test. Significance indicators: ns (not significant), p ≤ 0.05 (*), p < 0.01 (**), p ≤ 0.001 (***). p ≤ 0.0001 (****).

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