Table 2 PET indices by clinical diagnosis.

From: Potential utility of salivary gland amyloid uptake as a surrogate marker for adipose tissue and amyloid-beta dynamics based on its association with BMI and cerebral amyloid burden

 

Clinical diagnosis

Total

Aβ−CN

Aβ+MCI

Aβ+D

p-value

PET indices

 SUVRSG

2.16 (1.91, 2.47)

2.23 (1.97, 2.58)

2.04 (1.88, 2.25)

2.09 (1.78, 2.3)

0.0049*

 VolSG

23.91 (17.11, 31.13)

23.27 (16.86, 30.19)

24.86 (17.45, 32.23)

23.26 (14.83, 30.28)

0.6023

 SUVRB

1.37 ± 0.25

1.19 ± 0.05

1.62 ± 0.19

1.67 ± 0.17

p < 0.001*

 SUVRF

1.36 ± 0.27

1.18 ± 0.06

1.63 ± 0.21

1.67 ± 0.19

p < 0.001*

 SUVRPCu

1.3 (1.24, 1.77)

1.26 (1.21, 1.29)

1.86 (1.61, 2.01)

1.9 (1.7, 2.06)

p < 0.001*

 SUVRCg

1.46 ± 0.29

1.26 ± 0.07

1.76 ± 0.22

1.79 ± 0.23

p < 0.001*

 SUVRLP

1.38 ± 0.27

1.20 ± 0.07

1.65 ± 0.19

1.72 ± 0.18

p < 0.001*

 SUVRLT

1.27 ± 0.23

1.11 ± 0.05

1.49 ± 0.19

1.56 ± 0.16

p < 0.001*

 SUVROC

1.28 (1.21, 1.42)

1.23 (1.19, 1.28)

1.43 (1.32, 1.56)

1.5 (1.37, 1.62)

p < 0.001*

 SUVRStr

1.47 ± 0.2

1.36 ± 0.09

1.66 ± 0.18

1.64 ± 0.18

p < 0.001*

  1. Continuous variables are presented as mean ± standard deviation for normally distributed data and as median (interquartile range) for non-normally distributed data. Categorical variables are expressed as counts and percentages.
  2. SUVRSG standardized uptake value ratio of salivary gland, VolSG volume of salivary gland, SUVRB global standardized uptake value ratio of brain, SUVRF standardized uptake value ratio of frontal cortex, SUVRPCu standardized uptake value ratio of precuneus, SUVRCg standardized uptake value ratio of cingulate cortex, SUVRLP standardized uptake value ratio of lateral parietal cortex, SUVRLT standardized uptake value ratio of lateral temporal cortex, SUVROC standardized uptake value ratio of occipital cortex, SUVRStr standardized uptake value ratio of striatum, Aβ−CN amyloid-negative cognitively unimpaired, Aβ+MCI amyloid-positive mild cognitive impairment, Aβ+D amyloid-positive dementia.
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