Retraction of: Scientific Reports https://doi.org/10.1038/s41598-021-88133-7, published online 21 April 2021
The Editors have retracted this Article. After publication irregularities have been identified in the presented figures, specifically:
The Authors provided data files to address these concerns; however, the Editors were unable to validate these files as original data. The Editors therefore no longer have confidence in the reliability of the results presented in this Article.
Hongxing Yang and Lingeng Lu have not responded to correspondence from the Editors about this retraction. Rui Han and Lizhu Lin have not explicitly stated if they agree or disagree with this retraction.
References
Han, R. et al. MicroRNA-34a suppresses aggressiveness of hepatocellular carcinoma by modulating E2F1, E2F3, and caspase-3. Cancer Manag Res. 10(11), 2963–2976. https://doi.org/10.2147/CMAR.S202664 (2019).
Han, R., Nusbaum, O., Chen, X. & Zhu, Y. Valeric acid suppresses liver cancer development by acting as a novel HDAC inhibitor. Mol Ther Oncolytics. 29(19), 8–18. https://doi.org/10.1016/j.omto.2020.08.017 (2020).
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Han, R., Yang, H., Lu, L. et al. Retraction Note: Tiliroside as a CAXII inhibitor suppresses liver cancer development and modulates E2Fs/Caspase-3 axis. Sci Rep 15, 27590 (2025). https://doi.org/10.1038/s41598-025-11770-9
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DOI: https://doi.org/10.1038/s41598-025-11770-9
