Fig. 7
From: Sex dependent effects of GPR109A gene deletion in myeloid cells on bone development in mice
Cre recombinase male specific effect is also observed in 3-point bending analysis results. (A) For males, 3-point bending analysis of femur from 12-month old mice reveals significant increases in Yield Stress, Ultimate Stress and Elastic Modulus for both Cre+ and CKO mice compared to f/f mice. (B) For females, 3-point bending analysis of 12-month old femur shows no significant changes in Yield Stress, Ultimate Stress and Elastic Modulus between f/f, Cre+ or CKO mice. For One-way ANOVA, *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, **** P ≤ 0.0001.
