Fig. 2
From: Chlorogenic acid attenuates cardiac hypertrophy and fibrosis by downregulating galectin 3
Chlorogenic acid prevented cardiac hypertrophy in a mouse model of isoproterenol-induced cardiac hypertrophy. (A) Representative gross heart image. Scale on the ruler represents 1 mm. (B–C) Heart weight-to-body weight ratio and heart weight-to-tibia length ratio in three animal groups (n = 9–10 per group). ***P < 0.001; ###P < 0.001. (D) Representative H&E-stained heart tissues (n = 5–6 per group). Top panel: Low magnification (Scale bar = 1000 μm). Bottom panel: High magnification (Scale bar = 50 μm). (E) Quantification of cardiomyocyte area in heart tissues (n = 5–6 per group). (F) Representative wheat germ agglutinin-stained heart tissues. Top panel: Low magnification (Scale bar = 1000 μm). Bottom panel: High magnification (Scale bar = 50 μm). ***P < 0.001; ###P < 0.001. ISO; isoproterenol, CGA; chlorogenic acid.
