Table 1 Study population.

From: Blood platelet reduction after elexacaftor/tezacaftor/ivacaftor treatment in people with cystic fibrosis may depend on systemic inflammation reduction

 

N

males

females

age

CFHBI

  

n and (%)

n and (%)

median and IQR

 

pwCF:

272

135 (49.6)

137 (51.4)

25 (15-36)

86 (31.6)

- from Campania

132

60 (45.5)

72 (54.5)

29 (17-38)

31 (23.5)

- from Tuscany

140

75 (53.6)

65 (46.4)

21 (19-33)

55 (39.3)

Adult subjects:

166

87 (52.4)

79 (47.6)

33 (27-42)

53 (31.9)

- F508del homozygous

61

31 (50.8)

30 (49.2)

32 (25-38)

19 (31.1)

- F508del double heterozygous

105

56 (53.3)

49 (46.7)

33 (28-47)

13 (12.3)

Pediatric subjects:

106

48 (45.3)

58 (54.7)

14 (11-16)

33 (31.1)

- F508del homozygous

45

20 (44.4)

25 (55.6)

13 (11-16)

13 (28.9)

- F508del double heterozygous

61

28 (45.9)

33 (54.1)

14 (12-16)

20 (32.8)

Adult healthy controls

166

87 (52.4)

79 (47.6)

33 (27-42)

 

Pediatric healthy controls

106

48 (45.3)

58 (54.7)

14 (11-16)

 
  1. IQR: interquartile range; pwCF: people with cystic fibrosis; CFHBI: CF hepatobiliary involvement.