Table 2 Donor demographics, microstructural and mechanical data for fracture and non-fracture cohorts.

From: Runaway resorption of microcracks contributes to age-related hip-fracture patients

 

Non-fracture controls

Hip-fracture

p

Mean age (yrs) (SD)

78.6 (5.6)

77.8 (3.4)

0.775

Female, proportion (%)

4 (80.0)

5 (100.0)

n/a

Male, proportion (%)

1 (20.0)

0 (0.0)

n/a

Resorption pit (density/mm3)

0.28

0.28

0.774

Resorption trench (density/mm3)

0.12

2.10

< 0.001

Partially resorbed cracks (density/mm3)

0.24

1.19

< 0.001

Microcrack (density/mm3)

0.48

3.46

< 0.001

Ultimate tensile strength (MPa) (SD)

49.22 (5.73)

30.80 (4.59)

< 0.001

Young’s modulus (GPa) SD)

7.51 (1.86)

5.34 (1.58)

0.146

  1. Values are presented as mean and (StDev), compared using unpaired t-test. There was a significant increase in the density of resorption trenches, microcracks and partially resorbed microcracks in the fracture group, as well as a significant reduction in UTS in the fracture group. Young’s modulus was similar between the fracture group and the control.