Fig. 5
From: The immune-related prognostic gene AIM2 promotes pancreatic cancer progression via inflammasome
AIM2 enhances proliferation, migration, and invasion of pancreatic cancer cells. (A) qRT-PCR assessment of AIM2 overexpression efficiency in pancreatic cancer cells. (B) qRT-PCR assessment of AIM2 knockdown efficiency in pancreatic cancer cells. (C) Scratch assay conducted in pancreatic cancer Panc-1 cells: Left panel: Representative image of the scratch assay. Right panel: Statistical results of the scratch assay following AIM2 overexpression. **, P < 0.01, experiment repeated three times. (D) Transwell invasion and migration analysis in pancreatic cancer Panc-1 and Bxcp-3 cells: Left panel: Representative images of the Transwell invasion and migration experiments. Right panel: Statistical results of the Transwell invasion experiment. **, P < 0.01, ***, P < 0.001, experiment repeated three times. (E) Colony formation assay in pancreatic cancer Panc-1 and Bxcp-3 cells: Left panel: Representative image of the colony formation assay. Right panel: Statistical results of the colony formation assay following AIM2 overexpression. **, P < 0.01, experiment repeated three times.
