Table 2 Comparison of collagen content and the expression of transforming growth factor-beta1, α-smooth muscle actin and interleukin 6 among three groups.

From: Comparison of barbed suture and nonbarbed suture for laparoscopic cholecystoduodenostomy in rabbits: a randomized controlled trial

Group

CVF (%)

TGF-β1

α-SMA

IL-6

Day3

SFB group(n = 5)

15.09 ± 1.14

0.17 ± 0.03

0.21 ± 0.03

0.23 ± 0.03

SSB group(n = 5)

14.88 ± 0.89

0.16 ± 0.03

0.18 ± 0.02

0.17 ± 0.01

PDS group(n = 5)

13.79 ± 1.11

0.15 ± 0.02

0.20 ± 0.02

0.17 ± 0.01

p-value

0.153

0.507

0.175

 < 0.001*

pA-B

0.986

0.860

0.249

0.018B

pA-C

0.284

0.597

0.669

0.017C

pB-C

0.331

0.971

0.771

0.927

Day7

SFB group(n = 4)

28.53 ± 3.46

0.32 ± 0.04

0.31 ± 0.01

0.32 ± 0.03

SSB group(n = 5)

25.84 ± 1.45

0.21 ± 0.05

0.23 ± 0.01

0.24 ± 0.01

PDS group(n = 5)

25.74 ± 1.87

0.23 ± 0.06

0.23 ± 0.01

0.25 ± 0.02

p-value

0.178

0.038*

 < 0.001*

 < 0.001*

pA-B

0.528

0.037B

 < 0.001B

0.036B

pA-C

0.513

0.173

 < 0.001C

0.044C

pB-C

1.000

0.911

0.894

0.703

Day14

SFB group(n = 4)

46.68 ± 3.10

0.29 ± 0.03

0.34 ± 0.02

0.22 ± 0.01

SSB group(n = 5)

43.47 ± 2.86

0.23 ± 0.03

0.26 ± 0.01

0.19 ± 0.02

PDS group(n = 5)

44.38 ± 4.05

0.23 ± 0.04

0.27 ± 0.02

0.18 ± 0.01

p-value

0.389

0.075

 < 0.001*

0.003*

pA-B

0.405

0.120

0.001B

0.034B

pA-C

0.745

0.201

0.001C

0.014C

pB-C

0.971

0.998

0.715

0.947

  1. * p value of < 0.05.
  2. A P < 0.05 vs SFB group. B P < 0.05 vs SSB group. C P < 0.05 vs PDS group.
  3. CVF, collagen volume fraction; TGF-β1, transforming growth factor-beta1; α-SMA, α-smooth muscle actin; IL-6, interleukin 6.