Table 2 Cox regression model of TyG-related indexes and risk of MAFLD.

From: Relationship between triglyceride and glucose related indexes and MAFLD in rural populations of northwest China

Variable

MAFLD Events

Person-years

Incidence

(%)

MAFLD/Per

1,000 person-years

Model 1

Model 2

HR(95%CI)

P-value

HR(95%CI)

P-value

TyG*

Ā Ā Ā Ā 

1.280(1.141,1.436)

 < 0.001

1.196(1.060,1.350)

0.004

 ≤ 8.04

128

15,316.8

4.8

8.4

Reference

Ā Ā Ā 

8.05 ~ 8.48

144

15,273.8

5.4

9.4

1.217(0.958,1.545)

0.107

1.078(0.845,1.376)

0.545

8.49 ~ 8.85

142

15,269.0

5.3

9.3

1.227(0.966,1.560)

0.094

1.079(0.845,1.378)

0.541

 ≄ 8.86

182

15,161.1

6.8

12

1.547(1.233,1.940)

 < 0.001

1.363(1.075,1.729)

0.011

TyG-BMI*

Ā Ā Ā Ā 

1.014(1.013,1.016)

 < 0.001

1.013(1.012,1.015)

 < 0.001

 ≤ 181.79

29

15,454.4

1.1

1.9

Reference

Ā Ā Ā 

181.80 ~ 209.45

103

15,391.1

3.8

6.7

3.013(1.994,4.554)

 < 0.001

2.635(1.739,3.993)

 < 0.001

209.46 ~ 240.02

165

15,241.6

6.2

10.8

4.532(3.048,6.739)

 < 0.001

3.897(2.607,5.826)

 < 0.001

 ≄ 240.03

299

14,933.5

11.2

20

8.693(5.929,12.764)

 < 0.001

6.993(4.726,10.348)

 < 0.001

TyG-WC*

Ā Ā Ā Ā 

1.003(1.002,1.003)

 < 0.001

1.002(1.002,1.003)

 < 0.001

 ≤ 660.92

72

15,559.1

2.7

4.6

Reference

Ā Ā Ā 

660.93 ~ 750.15

100

15,201.0

3.8

6.6

1.273(0.940,1.725)

0.119

1.225(0.902,1.664)

0.195

750.16 ~ 845.88

181

15,198.9

6.8

11.9

2.077(1.576,2.735)

 < 0.001

1.872(1.408,2.488)

 < 0.001

 ≄ 845.89

243

15,061.6

9.1

16.1

2.980(2.287,3.881)

 < 0.001

2.540(1.918,3.364)

 < 0.001

TyG-WHtR*

Ā Ā Ā Ā 

1.563(1.452,1.682)

 < 0.001

1.438(1.324,1.562)

 < 0.001

 ≤ 4.02

71

15,416.7

2.7

4.6

Reference

Ā Ā Ā 

4.03 ~ 4.59

89

15,361.4

3.3

5.8

1.149(0.840,1.570)

0.385

1.076(0.785,1.474)

0.649

4.60 ~ 5.22

163

15,236.6

6.1

10.7

1.938(1.464,2.565)

 < 0.001

1.630(1.220,2.179)

0.001

 ≄ 5.23

273

15,005.8

10.2

18.2

3.246(2.495,4.223)

 < 0.001

2.541(1.917,3.369)

 < 0.001

  1. Model 1: non-adjusted model 1; Model 2: Adjusted by age group, sex, TC, HDL-C, LDL-C, SCr, education, marital status, smoking, drinking, and movement. TyG, triglyceride and glucose index; BMI, body mass index; WC, waist circumference; WHtR, waist-to-Height Ratio. *Indicates that the cumulative incidence rate between the groups is statistically significant. P < 0.05.