Fig. 2
From: Vertical transmission of chronic wasting disease in free-ranging white-tailed deer populations
CWD detection in white-tailed deer (WTD) fetal tissues determined by RT-QuIC. Amyloid seeding detected in fetal brain, thymus, and liver (Table 2) collected from CWD-positive dams as determined by RT-QuIC and IHC (Table 1). Amyloid formation displayed as reaction rates (1/time (t) to Thioflavin T (ThT) fluorescent threshold). Horizontal lines represent medians with n = 16 replicates (fetal tissues). Negative control fetal tissue samples from WTD collected in Georgia (n = 3) remained negative in all samples tested. P values as follows: * <0.05, ** <0.01, *** <0.001, ****<0.0001. Grey shaded rectangles denote samples utilized for bioassay inoculations (Table 4). Abbreviations represented as follows: (Th)ymus, (Br)ain, and (Liv)er.
