Table 1 GREAT pathway terms from analysis of TCF21 binding peaks.

GO molecular function

Growth factor binding

4.97E−23

4.58E−21

2.86

Protease binding

2.82E−16

2.13E−14

3.04

Ras GTPase binding

6.76E−15

4.45E−13

2.17

Insulin-like growth factor binding

3.67E−11

1.80E−09

3.65

Transforming growth factor beta binding

1.19E−09

5.14E−08

4.91

Extracellular matrix binding

1.28E−06

3.97E−05

2.02

GO biological process

Extracellular structure organization

4.12E−50

6.33E−48

2.60

Regulation of cell motility

1.06E−35

8.90E−34

2.02

Regulation of cell migration

9.38E−35

7.47E−33

2.03

Inflammatory response

2.94E−28

1.76E−26

2.02

Response to oxygen levels

3.22E−27

1.88E−25

2.30

Response to decreased oxygen levels

9.56E−26

5.17E−24

2.30

Response to hypoxia

2.16E−25

1.14E−23

2.30

Angiogenesis

1.44E−23

6.73E−22

2.03

GO cellular component

Proteinaceous extracellular matrix

1.27E−39

5.35E−38

2.25

Extracellular matrix

5.02E−39

1.99E−37

2.09

Extracellular matrix part

5.60E−30

1.97E−28

2.52

Extracellular membrane-bounded organelle

5.76E−27

1.62E−25

3.47

MSigDB pathway

Betal integrin cell surface interactions

2.58E−32

3.40E−29

4.11

Focal adhesion

1.42E−25

9.39E−23

2.39

ECM-receptor interaction

6.08E−19

1.34E−16

2.89

Integrins in angiogenesis

1.56E−17

2.93E−15

2.96

Genes involved in Integrin cell surface interactions

1.13E−16

1.66E−14

2.86

Genes involved in Collagen formation

1.12E−15

1.24E−13

3.13

HIF-1 -alpha transcription factor network

4.97E−15

4.68E−13

2.80

Genes involved in Extracellular matrix organization

3.92E−14

3.24E−12

2.56

Genes involved in Signaling by PDGF

4.49E−14

3.48E−12

2.29

PDGFR-beta signaling pathway

8.02E−11

4.23E−09

2.01

MAPKinase Signaling Pathway

3.92E−10

1.72E−08

2.25

IL6-mediated signaling events

8.08E−08

1.78E−06

2.42

PANTHER pathway

Integrin signaling pathway

9.28E−25

1.41E−22

2.49

TGF-beta signaling pathway

1.17E−09

4.43E−08

2.18

p38 MAPK pathway

1.05E−08

3.18E−07

2.91