Fig. 4

Associations between gray matter volume and pain duration. Group-stratified results are shown for bivariate associations between mean C5 – C7 ventral (A) and dorsal (B) horn gray matter volumes (GMVs) and average pain duration in years. FMO = individuals with fibromyalgia taking opioids; FMN individuals with fibromyalgia not taking opioids, Rs Spearman’s correlation coefficient. Statistical significance threshold set at p < 0.05. Lines representing the correlation trends that met this threshold are solid and bold.