Table 1 Demographic characterization of the cohort. Fisher’s exact test and Kruskal–Wallis’s test were used for categorical and continuous variables, respectively.
Alzheimer (n = 50) | Control (n = 50) | True (N = 100) | P value | |
|---|---|---|---|---|
Gender | 0.8264 | |||
F | 35 (70.0%) | 36 (72.0%) | 71 (71.0%) | |
M | 15 (30.0%) | 14 (28.0%) | 29 (29.0%) | |
Age range | 1.20E-05 | |||
55–65 | 3 (6.0%) | 16 (32.0%) | 19 (19.0%) | |
66–76 | 19 (38.0%) | 27 (54.0%) | 46 (46.0%) | |
> 77 | 28 (56.0%) | 7 (14.0%) | 35 (35.0%) | |
Education | 0.0002382 | |||
< 12 | 9 (18.0%) | 0 (0.0%) | 9 (9.0%) | |
12 | 12 (24.0%) | 4 (8.0%) | 16 (16.0%) | |
> 12 | 29 (58.0%) | 46 (92.0%) | 75 (75.0%) | |
B12 | 0.4061 | |||
Mean (SD) | 885 (534) | 668 (424) | 795 (500) | |
Median [Min, Max] | 777 [242, 2470] | 454 [165, 1660] | 624 [165, 2470] | |
Missing | 12 (24.0%) | 23 (46.0%) | 35 (35.0%) | |
BMI range | 0.01469 | |||
Normal (< 25) | 18 (36.0%) | 12 (24.0%) | 30 (30.0%) | |
Overweight (25–29.9) | 21 (42.0%) | 13 (26.0%) | 34 (34.0%) | |
Obese (≥ 30) | 11 (22.0%) | 25 (50.0%) | 36 (36.0%) | |
CDR range | 2.2E-16 | |||
No Dementia (0) | 4 (8.0%) | 49 (98.0%) | 53 (53.0%) | |
Very Mild Dementia (0.5) | 14 (28.0%) | 1 (2.0%) | 15 (15.0%) | |
Moderate to Severe Dementia (1–3) | 32 (64.0%) | 0 (0.0%) | 32 (32.0%) | |
MoCA range | 8.28E-09 | |||
Normal Cognition (26—30) | 0 (0%) | 6 (12.0%) | 6 (6.0%) | |
Mild cognitive impairment (18–25) | 13 (26.0%) | 36 (72.0%) | 49 (49.0%) | |
Moderate cognitive impairment (10–17) | 15 (30.0%) | 8 (16.0%) | 23 (23.0%) | |
Severe cognitive impairment (≤ 9) | 22 (44.0%) | 0 (0.0%) | 22 (22.0%) | |
APOE Genotype | 0.51 | |||
E2E3 | 4 (8.0%) | 2 (4.0%) | 6 (6.0%) | |
E3E3 | 27 (54.0%) | 34 (68.0%) | 61 (61.0%) | |
E3E4 | 17 (34.0%) | 13 (26.0%) | 30 (30.0%) | |
E4E4 | 2 (4.0%) | 1 (2.0%) | 3 (3.0%) |
