Table 1 Effects of zinc intake on the weight, blood chemistry and urine chemistry in the study groups.
From: Zinc alleviates vascular calcification by activating ERK1/2-mediated autophagy
CTR(n = 8) | CTR + Zn(n = 8) | CKD(n = 8) | CKD + Zn(n = 8) | |
---|---|---|---|---|
Weight (g) | 423.38 ± 23.82 | 412.13 ± 16.97 | 311.25 ± 15.83a | 318.88 ± 21.95a |
SCr (μmol/L) | 65.12 ± 20.08 | 60.59 ± 22.32 | 511.21 ± 60.76a | 420.16 ± 80.37a,b |
SCa (mmol/L) | 2.49 ± 0.12 | 3.24 ± 0.16 | 1.65 ± 0.14a | 2.07 ± 0.12a,b |
SP (mmol/L) | 2.42 ± 0.29 | 2.68 ± 0.26 | 7.62 ± 0.16a | 5.58 ± 0.31a,b |
SZn (μmol/L) | 19.49 ± 0.92 | 19.11 ± 0.45 | 19.25 ± 1.70 | 17.79 ± 1.14 |
UCa (mg/24 h) | 1.01 ± 0.65 | 1.22 ± 0.41 | 1.81 ± 0.82a | 1.49 ± 0.57a,b |
UP (mg/24 h) | 126.67 ± 88.32 | 152.22 ± 72.16 | 70.05 ± 15.83a | 78.29 ± 27.52a |
PTH (pg/mL) | 22.24 ± 6.51 | 19.23 ± 5.76 | 602.18 ± 97.92a | 80.50 ± 16.31a,b |
sRANKL (pg/mL) | 95.41 ± 20.32 | 93.56 ± 22.19 | 178.83 ± 23.40a | 133.25 ± 19.66a,b |
PINP (pg/mL) | 158.32 ± 23.25 | 155.43 ± 25.38 | 307.44 ± 31.69a | 232.15 ± 28.64a,b |
CTX-I (pg/mL) | 56.93 ± 9.6 | 55.85 ± 8.2 | 86.12 ± 12.24a | 73.57 ± 9.3a,b |