Table 3 Hazard ratio of mucus plug presence for various histology of lung cancer.
From: Mucus plug and lung cancer incidence in patients with COPD
Non-small cell lung cancer | Squamous cell carcinoma | Adenocarcinoma | ||||
---|---|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
Unadjusted model | 2.594 (1.370–4.911) | 0.003 | 3.757 (1.596–8.841) | 0.002 | 1.431 (0.519–3.948) | 0.489 |
Adjusted model | ||||||
+ Age | 2.373 (1.252–4.498) | 0.008 | 3.391 (1.439–7.993) | 0.005 | 1.340 (0.485–3.706) | 0.573 |
+ Sex | 2.150 (1.130–4.090) | 0.020 | 3.104 (1.308–7.365) | 0.010 | 1.202 (0.433–3.333) | 0.724 |
+ Smoking history | 2.008 (1.051–3.838) | 0.035 | 2.935 (1.229–7.008) | 0.015 | 1.204 (0.434–3.343) | 0.722 |
+ Pack years | 1.980 (1.036–3.784) | 0.039 | 2.891 (1.211–6.904) | 0.017 | 1.227 (0.439–3.425) | 0.696 |
+ Blood neutrophil (%) | 2.073 (1.081–3.976) | 0.028 | 3.094 (1.293–7.402) | 0.011 | 1.222 (0.437–3.421) | 0.702 |
+ Post-bronchodilator FEV1/FVC | 2.098 (1.088–4.046) | 0.027 | 3.076 (1.278–7.402) | 0.012 | 1.256 (0.444–3.553) | 0.668 |
+ History of asthma | 2.011 (1.041–3.887) | 0.038 | 2.899 (1.202–6.991) | 0.018 | 1.197 (0.423–3.388) | 0.734 |
+ History of pulmonary tuberculosis | 2.078 (1.074–4.021) | 0.030 | 3.057 (1.265–7.390) | 0.013 | 1.193 (0.420–3.389) | 0.741 |
+ Charlson comorbidity index | 1.893 (0.967–3.706) | 0.063 | 2.985 (1.207–7.383) | 0.018 | 1.010 (0.350–2.914) | 0.985 |