Fig. 6

Morphology of CRC MCTSs generated in CR-plates and anti-adherence treated MT-plates. (A) Representative images of MCTS from the 8 CRC cell lines in CR-Plates (left) and anti-adherence treated MT-Plates (right), in Matrigel. The complete set of pictures are provided in the Supplementary File TimeSeries.zip. (B) Morphological analysis of MCTSs shown in panel A. P-values indicate the statistical significance of the effect of the type of plate (CR-Plate vs. MT-Plate) after correcting for time (multivariate linear regression, with time and plate type as explanatory variables).