Table 1 Clinical characteristics of the study participants.
From: Metabonomics of serum bile acids in patients with pre-eclampsia
Variables | Pre-eclamptic patients (n = 30) | Healthy pregnancy (n = 30) | p-value |
|---|---|---|---|
Age (y) | 34 ± 4.4 | 32 ± 3.7 | 0.0995 |
Gestational age (wk) | 30[27,34] | 31[27,34] | 0.9265 |
Pre-pregnancy BMI(kg/m2) | 23.84 ± 4.228 | 21.72 ± 2.806 | 0.0266* |
First delivery | 17(56.67%) | 25(83.33%) | 0.0486* |
Blood pressure | |||
Systolic blood pressure(mmHg) | 138.5[123.5,147.0] | 116.5[108.5,126.8] | < 0.0001*** |
Diastolic blood pressure(mmHg) | 84.5[76.8,89.3] | 70[61.0,79.3] | 0.0002*** |
Mean arterial pressure(mmHg) | 86.82 ± 8.997 | 86.66 ± 11.29 | 0.9514 |
Biochemical characteristics | |||
Albumin(g/L) | 32.8[29.7,36.5] | 35.65[33.7,36.7] | 0.0106* |
Creatinine(µmol/L) | 54.63 ± 11.73 | 49.87 ± 7.422 | 0.066 |
Glycocholic acid(µg/ml) | 1.93[1.45,2.96] | 1.67[1.42,2.09] | 0.2012 |
Total bile acid(µmol/L) | 2.40[1.20,3.73] | 1.85[1.28,2.63] | 0.2089 |
Medical records | |||
Diabetes | 4(13.33%) | 5(16.67%) | > 0.9999 |
Kidney injury | 3(10.00%) | 2(6.67%) | > 0.9999 |
Assisted reproductive technology | 7(23.33%) | 1(3.33%) | 0.0576 |
Antiphospholipid syndrome | 1(3.33%) | 0(0%) | > 0.9999 |
Early-onset pre-eclampsia | 21(70.00%) |
