Table 5 Comparison of the presence or absence of ascites and adverse events.

From: Efficacy and safety of taxane plus ramucirumab for advanced gastric cancer after chemotherapy plus nivolumab

 

All (n = 51)

With ascites (n = 26)

Without ascites (n = 25)

p

All

Grade3 or more

All

Grade3 or more

All

Grade3 or more

All

Grade3 or more

Neutropenia

33 (65%)

21 (41%)

19 (73%)

13 (50%)

14 (56%)

8 (32%)

0.7712

0.7793

Anemia

10 (20%)

5 (10%)

8 (31%)

3 (12%)

2 (8%)

2 (8%)

0.0751

0.3497

Platelet decreased

3 (6%)

1 (2%)

2 (8%)

1 (4%)

1 (4%)

0

1

1

Febrile neutropenia

4 (8%)

4 (8%)

3 (12%)

3 (12%)

1 (4%)

1 (4%)

0.6098

0.6098

Peripheral sensory neuropathy

21 (42%)

0

8 (31%)

0

13 (52%)

0

0.1599

 

Fatigue

15 (30%)

0

8 (31%)

0

7 (28%)

0

0.7544

 

Anorexia

9 (20%)

1 (2%)

6 (23%)

1 (4%)

3 (12%)

0

0.0751

1

Stomatitis

5 (10%)

1 (2%)

4 (15%)

1 (4%)

1 (4%)

0

0.1104

1

Bleeding

5 (10%)

0

3 (12%)

0

2 (8%)

0

0.6098

 

Edema

2 (4%)

0

1 (4%)

0

1 (4%)

0

1

 

Proteinuria

3 (6%)

3 (6%)

3 (12%)

3 (12%)

0

0

0.2353

0.2353

Hypertension

2 (4%)

1 (2%)

2 (8%)

0

2 (8%)

1 (4%)

0.1104

0.4902

Infection

3 (6%)

2 (4%)

1 (4%)

0

1 (4%)

0

1

1