Table 3 The peripheral blood inflammatory cell count results upon admission for COVID-19 patients and controls.

From: TIPE2 suppresses ferroptosis and pro-inflammatory polarization in macrophages triggered by SARS-CoV-2 spike protein

Blood parameter counts

Covid−19 group (n = 44)

Control group (n = 11)

P value

Critical (n = 22)

Moderate-Severe (n = 22)

Neutrophils (1.8–6.3 × 109/L)

7.18* (5.50,14.12)

5.86 (2.78, 9.60)

4.04 (3.29, 5.02)

0.013

< 1.8

1/22 (4.5%)

1/22 (4.5%)

0

1.8–6.3

7/22 (31.8%)

10/22 (45.5%)

11/11(100%)

> 6.3

14/22 (63.6%)

11/22 (50.0%)

0

Lymphocytes (1.1–3.2 × 109/L)

0.30** (0.20, 0.55)

0.65** (0.38, 1.13)

2.49 (1.78, 2.82)

< 0.001

< 1.1

22/22 (100%)

16/22 (72.7%)

0

≥ 1.1

0

6 /22(27.3%)

11/11(100%)

NLR

28.38**,# (15.12, 49.13)

9.19** (4.30, 18.65)

1.96 (1.55, 2.22)

< 0.001

Monocytes (0.1–0.6 × 109/L)

0.30 (0.20, 0.48)

0.40 (0.28, 0.53)

0.40 (0.20, 0.50)

< 0.6

17/22 (77.3%)

17/22 (77.3%)

11/11(100%)

≥ 0.6

5/22 (22.7%)

5/22 (22.7%)

0

Eosinophils (0.02–0.52 × 109/L)

0**

0.01** (0, 0.03)

0.32 (0.18, 0.48)

< 0.001

0

17/22 (77.3%)

10/22 (45.5%)

0

< 0.02

4 /22(18.2%)

5/22(22.7%)

0

≥ 0.02

1 /22(4.5%)

7 /22(31.8%)

11/11(100%)

-

  1. Data are reported as median (IQR) or n/N (%); N denotes the total number of individuals with available information.
  2. P values comparing the groups are from ANOVA or Kruskal–Wallis test.
  3. P < 0.05: * vs. Control group, # vs. Moderate-Severe group.
  4. P < 0.01: ** vs. Control group, ## vs. Moderate-Severe group.
  5. NLR neutrophil-to-lymphocyte ratio.