Fig. 3
From: Pirfenidone combined with UC-MSCs reversed bleomycin-induced pulmonary fibrosis
UC-MSCs with PFD reverse histopathological damage. (a) H&E and Masson trichome staining (n = 6). Scale bars are 1000 and 200 μm. (b, d) WB analysis of α-SMA, collagen I, SMAD2/3, and p-SMAD2/3 (n = 3). Original gels were presented in Supplementary Figs. 1 and 2. (c) Inflammatory scores and Ashcroft scores (n = 6). Data were expressed as means ± SD. The significant difference was analyzed by the letter-based method. Groups that share at least one common letter were considered not significantly different from each other, while groups with completely different letters were considered significantly different. (P < 0.05). Abbreviations: PFD: pirfenidone. PFD + Low: PFD + Low UC-MSCs. PFD + Medium: PFD + Medium UC-MSCs. PFD + High: PFD + High UC-MSCs. Low: Low UC-MSCs. Medium: Medium UC-MSCs. High: High UC-MSCs.
