Fig. 1
From: Prediction of CD8+ T cell infiltration in the tumor microenvironment of HGSOC patients
Localization, infiltration patterns of CD8+ T cells in ovarian cancer tissues and their prognostic significance. (A) The tumor area was defined by detecting CK expression using mIHC. The CK-positive area is the tumor parenchyma, and the CK-negative area is the tumor stroma. (B) Significant heterogeneity in infiltration patterns was observed based on the localization of CD8+ T cells in the tumor parenchyma and stroma. (C) Kaplan–Meier survival curve analysis of the infiltration density of CD8+ T cells in different regions with patients’ overall survival. (Left) Infiltration density in the tumor stroma; (Middle) Infiltration density in the tumor parenchyma; (Right) Infiltration density in the entire tissue area (total).
