Table 2 Anti-urease activities of template compounds A-F and new compound 9 L.
Compound | IC50 (urease) | Standard inhibitor | IC50 (urease) | Xa |
|---|---|---|---|---|
A36 | 14.21 µM | Thiourea | 21.14 µM | 1.47 |
B37 | 14.04 µg/mL | Acetohydroxamic acid | 20.50 µg/mL | 1.46 |
C38 | 3.10 µM | Thiourea | 21.00 µM | 6.77 |
D39 | 1.41 µM | Thiourea | 22.56 µM | 16 |
E40 | 58.92 µM | Thiourea | 78.89 µM | 1.33 |
F41 | 2.10 µM | Thiourea | 36.40 µM | 17.33 |
9 L | 0.15 µM | Thiourea | 23.11 µM | 154 |
a: X = IC50 value of studied compound/IC50 value of standard inhibitor. | ||||
