Fig. 2
From: HPV vaccination improves immune response in children with respiratory papillomatosis

HPV vaccination is associated with improved clinical outcomes. Comparison of clinical parameters between unvaccinated (Unvax), single-dose (Vax-1), and fully vaccinated (Vax, 3 doses) patient groups. Data are presented for (a) the number of distinct anatomical zones affected by papilloma, (b) the mean number of surgeries required per year, (c) the mean time elapsed between surgical interventions, and (d) the overall surgery rate. Data are presented as mean ± SEM. Statistical significance was determined by unpaired t-test. *p < 0.05, ***p < 0.001.