Fig. 3
From: HPV vaccination improves immune response in children with respiratory papillomatosis
Vaccination induces HPV-specific IgG antibodies that negatively correlate with viral load. (a) Comparison of HPV-specific IgG antibody titers in fully vaccinated (Vax) versus unvaccinated (Unvax) patients. Viral load of (b) HPV6 and (c) HPV11 in lesional tissue from both patient cohorts. (d) Correlation analysis in vaccinated patients demonstrating a significant negative relationship between HPV-specific IgG titers and total HPV viral load (HPV6 + HPV11 copies/ng). The line represents the best linear fit. Pearson correlation coefficient (r) and p-value are indicated. Data in (a-c) are presented as mean ± SEM. Statistical significance was determined by unpaired t-test. *p < 0.05.
