Fig. 4 | Scientific Reports

Fig. 4

From: Co-administration of low-dose-Naltrexone and Carbamazepine remarkedly ameliorate allodynia and cognitive deficit in a rat model of trigeminal neuralgia

Fig. 4

Mechanical (A), facial cold allodynia (B) and air puff test (C) of Control, Sham, nontreated-TN, and treated-TN rats. Repeated measure analysis showed a significant difference in pain threshold in all the groups at 7, 14, and 22 days after surgery in comparison to the Control and Sham (P < 0.05). The mechanical allodynia threshold of TN (CBZ100 + LDN) rats was significantly higher than the threshold of the TN group in day 22 (P < 0.05). Results are shown as mean ± SEM (n = 8). *P < 0.05, **P < 0.01, ***P < 0.001 versus the Control, XP<0.05, XXP<0.01, XXXP<0.001 versus the Sham, and #P < 0.05, ##P < 0.01, ###P < 0.001 versus the TN rats.

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