Fig. 5 | Scientific Reports

Fig. 5

From: Co-administration of low-dose-Naltrexone and Carbamazepine remarkedly ameliorate allodynia and cognitive deficit in a rat model of trigeminal neuralgia

Fig. 5

Open field testing revealed that rearing time was significantly improved in treated TN rats with LDN (A). The TN rats showed increased face-grooming activities compared to Sham group. All treatment groups showed improvement in face-grooming activities (B). 7-day treatment with CBZ100 or CBZ100 + LDN increased the time spent in the central part of the open field compared to TN animals. Results are shown as mean ± SEM (n = 8). XXXP<0.001 versus the Sham operated group, and #P < 0.05, ##P < 0.01, ###P < 0.001 versus the TN rats and +P < 0.05, ++P < 0.01 versus CBZ 100 mg group.

Back to article page