Fig. 1

Chemical structure, and cell proliferation of CTXA treatment on A549 and NCI-H441 cells. (A) The chemical structure of CTXA. (B–E) The cell viability was detected by MTT assay. A549 cells were treated with various doses of CTXA for 24 h (B) or 48 h (C). NCI-H441 cells were treated with various doses of CTXA for 24 h (D) or 48 h (E). (F) Colony formation assay of A549 cells were treated with various doses of CTXA. (G) Quantification of clonogenic formation was analyzed. Data represent the average of three independent experiments (means ± SEM). *** p < 0.001 versus the control.