Fig. 2

Effect of CTXA on EGFR signaling pathway in A549 cells. (A) A549 cells were treated with various doses of CTXA for 1 h and then stimulated with EGF (20 ng/ml) for 5 min. (B–D) Quantification of the p-EGFR, p-AKT and p-Erk levels versus their relative total protein levels was analyzed. Data represent the average of three independent experiments (means ± SEM). ###p < 0.001 versus the control; **p < 0.01, ***p < 0.001 versus EGF.